CAUTION-Investigational Device. Limited by United States Law to Investigational Use.


Ongoing Studies1

Studies

The CARILLON Trial
 
If you have heart failure, you know how this condition affects your quality of life. Simple daily activities like preparing meals, visiting with friends, or even moving from room to room can require major effort and leave you exhausted. An estimated 26 million people suffer from heart failure worldwide, and the number is growing rapidly.

Nearly 75% of heart failure sufferers also have a leaky mitral valve, a condition known as mitral regurgitation (MR). Unfortunately, this further compromises the function of the heart – causing your heart failure to worsen over time.

If you struggle with heart failure symptoms or have been told you have a leaky valve, you may qualify for a new clinical study being offered at select US centers. The study is for the Carillon Mitral Contour System, an investigational implant designed to reshape the mitral valve and reduce leakage through a non-surgical approach.

Cardiac Dimensions is currently enrolling patients in our CARILLON Trial. Trial sites are currently located in the U.S., U.K., Poland, Greece and France. Enrolling trial sites can be viewed on the interactive map below. Please check back often as we add more sites regularly.

Interested patients may find out more about the trial at Clinical Trials (click here) and at New HF Trial (click here).

You can also contact Cardiac Dimensions at clinical@cardiacdimensions.com.

Study Locations

 


 


 



 


 

Ongoing Studies and Past Studies

Percutaneous Mitral Annuloplasty for Functional Mitral Regurgitation Results of the CARILLON Mitral Annuloplasty Device European Union Study
Schofer J, Siminiak T Haude M, Herrman JP, Vainer J, Wu JC, Levy WC, Mauri L, Feldman T, Kwong RY, Kaye D, Duffy SJ, Tübler T, Degen H, Brandt MC, Van Bibber R, Goldberg S, Reuter DG, Hoppe UC
Circulation 2009; 120: 326-333

Treatment of functional mitral regurgitation by percutaneous annuloplasty: results of the TITAN Trial
Siminiak, T, Wu JC, Haude M, Hoppe UC, Sadowski J, Lipiecki J, Fajadet J, Shah AM, Feldman T, Kaye DM, Goldberg SL, Levy WC, Solomon SD, Reuter DG
Eur J Heart Fail. 2012 Aug; 14(8): 931-8

Coronary sinus-based percutaneous annuloplasty as treatment for functional mitral regurgitation: the TITAN II trial
Lipiecki J, Siminiak T, Sievert H, et al
BMJ Open Heart. 2016; 3: e000411

A Randomized Sham-Controlled Study of Percutaneous Mitral Annuloplasty in Functional Mitral Regurgitation: The REDUCE FMR Trial.
Witte K, Lipiecki J, Siminiak T, et al.
J Am Coll Cardiol HF. DOI: 10.1016/j.jchf.2019.06.011