TCT 2022 Poster
Goldberg S et al.
2022
Prospective trials of the Carillon Mitral Contour System have shown effective hemodynamic and clinical improvement in patients with heart failure and functional mitral regurgitation (FMR) including beneficial left ventricular and left atrial remodeling.
The CINCH registry is a multi-center, real-world study of patients treated with the Carillon device as standard of care. It is intended to enroll up to 250 patients in up to 40 centers in Germany.
The poster presented shows an interim analysis of 101 patients with up to 5 years follow-up data, including mortality, device related safety, change in NYHA class and rate of heart failure hospitalizations.
Compared to baseline
>90%
MR grade improved after 5 years follow-up period
>50%
NYHA class and MR grade at least maintained after 5 years follow-up period
>80%
NYHA class improved after 5 years follow-up period
Mortality and HF hospitalization rate trending notably better than GDMT for 24 months